Caused by the monkeypox virus, mpox is transmitted by close contact between people or with infected animals. There are two clades – or strains – of the virus. It has been endemic in Central Africa and West Africa for over 50 years.

People with mpox experience rashes, lesions, and pain, all of which require supportive treatment for the symptoms. Most patients treated recover within a month; however, people with weakened immune systems, children and pregnant women are most at risk of serious illness or death.